【摘要】 目的  了解输卵管积水对体外授精结局的影响及最佳治疗方案。方法  对我院2001年9月至2002年12月接受体外授精―胚胎移植的所有采用长方案的输卵管性不孕的患者的136例临床资料进行回顾性分析，其中49例伴有输卵管积水，接受了52个周期治疗，均采用抗菌素和/或积水抽吸术和/或宫腔积液抽吸治疗，为观察组；87例不伴有输卵管积水，接受了92个周期治疗，为对照组。比较两组患者对促排卵的反应、胚胎种植率、临床妊娠率 、早期流产率及宫外孕的发生率。结果  观察组所用的FSH总支数、获卵数、受精数、种植率、妊娠率、早期流产率分别为46.54、19.42、12.83、16.1%、41.2%、14.3%，对照组所用的FSH总支数、获卵数、受精数、种植率、妊娠率、早期流产率分别为46.01、18.31、11.41、17.5%、40.7%、10.8%，结果相似；观察组宫外孕发生率为14.3%，对照组为8.1%，观察组有升高的趋势，但无统计学意义。结论  综合治疗输卵管积水对体外授精结局无不良影响。上海交通大学医学院附属第九人民医院辅助生殖科艾爱

　　【关键词】综合治疗  输卵管积水  体外授精结局

　　The effect of hydrosalpinx with combined treatment in IVF

　　【Abstract】  Objective  To determine the effect of the presence of the hydrosalpinx with combined treatment on the outcome with IVF-ET. Methods  136 patients witjh tubal disease were divided into two groups, in study group,49 patients with hydrosalpinx recepted 52 stimulation cycles, they were treated with antibiotics and/or drainage of hydrosalpinges and/or uterine fluid aspiration; in control group,87 patients with no hydrosalpinx recepted 92 stimulation cycles. Ample of FSH used, the number of ovum and fertilized ovum, implantation rate, clinical pregnancy rate and clinical abortion rate of the two groups were compared. Result  Ample of FSH used, the number of ovum and fertility ovum, implantation rate, clinical pregnancy rate and clinical abortion rate in study group were 46.54、19.42、12.83、16.1%、41.2%、14.3%, in control group were 46.01、18.31、11.41、17.5%、40.7%、10.8%,there were no significant difference. in study group,ectopic rate were 14.3%，in control group were 8.1%,had a rise tendcy,but no statistical discrepancy. Conclusion  the hydrosalpinx with combined treatment did not affect the outcome of IVF.

　　【Key words】  combined treatment   hydrosalpinx   the outcome of IVF