中华消化内镜杂志, 2005, 22(5):319-322

　　广东省糜烂性食管炎内镜检出率调查

　　李初俊　陈村龙　梁远国　黄开红　周宇　崔西玉　聂玉强　杨见权　郑丰平　刘婉薇　钟敏　丁元伟　陈惠新　陈F湖中山大学附属第六医院消化内镜中心李初俊

　　【摘要】　目的　通过分析13家医院内镜诊断的糜烂性食管炎的病例，探讨广东省糜烂性食管炎的患病情况。方法　回顾性分析广东省13家大医院2003年全年上消化道内镜检查的所有病例共63459例，以洛杉矶标准收集符合糜烂性食管炎诊断的病例的内镜资料及相关信息进行分析。结果　共检出糜烂性食管炎 1263例(年龄 3-90岁，平均年龄50.2±17.1)，糜烂性食管炎A、B、C、D级的检出率分别为0.94%（599/63459）、0.69%（440/63459）、0.21%（132/63459）和0.14%（92/63459），总检出率为1.99% (1263/63459)，其中A、B级患者占82.3%（1039/1263）。糜烂性食管炎的严重程度随着患者的年龄的增加而增加(F=22.932, p<0.001)。男性病例明显多于女性病例(男性882例，女性381例，男:女=2.3:1)。食管裂孔疝见于6.7%(85/1263)的病例，其平均年龄明显大于无食管裂孔疝患者(60.0±17.1 vs 49.5±16.8, p＜0.001)，但两组病变的严重程度情况相似。Barrett 食管及食管狭窄等并发症发生率不高(分别为0.71%和 0.63% )。 结论　广东省糜烂性食管炎的内镜检出率为1.99%，以轻中度的A、B级为主，并多见于男性、年长患者，病变严重程度随患者年龄的增加而增加，

　　【关键词】糜烂性食管炎；胃食管反流病；内镜检查

　　The prevalence of erosive esophagitis among consecutive patients who received endoscopy in Guangdong province of China LI Chu-jun*, CHEN Cun-long, LIANG Yuan-guo, et al. *Division of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080,China

　　【Abstract】Objective  To investigate the prevalence of erosive esophagitis (EE) among  consecutive patients who received endoscopy in Guangdong province of China. Methods  Retrospectively reviewed all the cases (63459 cases) who received oesophagogastrodeuodenoscopy in 13 main hospitals in Guangdong province of China in 2003. Los Angeles criteria for classification of erosive esophagitis was employed to review all the cases. Results  One thousand two hundreds and sixty-three patients (age range 3-90yr, mean 50.2±17.1) were found to have EE. The overall prevalence of EE was 1.99% (1263/63459). Age correlated on endoscopic grading of EE (F=22.932, p<0.001). Most of the patients (82.3%, 1039/1263) had a mild grade (grade A or grade B) of esophagitis. The male-to-female preponderance of EE was 2.3:1(882: 381). Hiatus hernia was found in 85 patients (6.7%) which were significantly older than those without hiatus hernia (60.0±17.1 vs 49.5±16.8, p＜0.001). But no difference in the distribution of severity of esophagitis was found between patients with and without hiatus hernia.

　　Complication such as Barrett esophagus or stricture was not common (0.71%, 0.63% respectively) in these patients. Conclusion  The prevalence of endoscopic erosive esophagitis among Chinese in Guangdong was 1.99%, the majority of which were mild, grade A or B. EE was more common in male and elderly patients. The severity of EE was correlated with the age of the patients.

　　【Key words】 Erosive esophagitis; Gastroesophageal reflux disease; Endoscopy